NLRP10 antibody (AA 401-500) (Alexa Fluor 555)

Catalog No. ABIN908448

Product Details anti-NLRP10 Antibody (Alexa Fluor 555)

Target: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Binding Specificity: AA 401-500

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP10 antibody is conjugated to Alexa Fluor 555

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NLRP10

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NLRP10

Target: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Alternative Name: NLRP10 (NLRP10 Products)

Synonyms: CLR11.1 antibody, NALP10 antibody, NOD8 antibody, PAN5 antibody, PYNOD antibody, 6430548I20Rik antibody, Nalp10 antibody, Napl10 antibody, Pynod antibody, NLR family pyrin domain containing 10 antibody, NLR family, pyrin domain containing 10 antibody, NLRP10 antibody, Nlrp10 antibody

Background:

Synonyms: CLR11.1, NACHT, leucine rich repeat and PYD containing 10, NACHT, LRR and PYD domains containing protein 10, NACHT, LRR and PYD domains-containing protein 10, NAL10_HUMAN, NALP10, NLR family, pyrin domain containing 10, Nlrp10, NOD8,Nucleotide-binding oligomerization domain protein 8, Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10, PAN5, PYNOD.

Background: Inhibits CASP1/caspase-1-dependent IL1B secretion and PYCARD-mediated apoptosis, but not that induced by FAS or BID.Tissue specificity: Widely expressed with highest levels in heart, brain and skeletal muscle.

Gene ID: 338322

Pathways: Inflammasome