Peroxiredoxin 1 antibody (PRDX1) (AA 63-88) (Alexa Fluor 488)

Details for Product anti-PRDX1 Antibody No. ABIN912097, Supplier: Log in to see
Antigen
  • CBP
  • PAG
  • MSP23
  • NKEF-A
  • NKEFA
  • PAGA
  • PAGB
  • PRX1
  • PRXI
  • TDPX2
  • NkefA
  • OSF-3
  • OSF3
  • Paga
  • PrdxI
  • PrxI
  • TDX2
  • TPxA
  • Tdpx2
  • prx1
  • Hbp23
  • MGC80194
  • MGC84820
  • PRDX1
  • msp23
  • nkefa
  • pag
  • paga
  • pagb
  • prx-1
  • prxi
  • tdpx2
  • hm:zehl0637
  • zgc:110343
  • TPX-2
  • phosphoprotein membrane anchor with glycosphingolipid microdomains 1
  • peroxiredoxin 1
  • peroxiredoxin 1 S homeolog
  • PAG1
  • PRDX1
  • Prdx1
  • prdx1.S
  • prdx1
Alternatives
anti-Human Peroxiredoxin 1 antibody for Immunofluorescence
Epitope
AA 63-88
52
14
14
8
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5
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4
4
3
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
196
59
54
7
7
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6
5
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4
4
3
1
1
1
1
1
Host
Rabbit
106
77
22
Clonality
Polyclonal
Conjugate
This Peroxiredoxin 1 antibody is conjugated to Alexa Fluor 488
13
13
9
4
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
169
108
51
22
18
16
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12
9
5
5
4
2
1
Options
Supplier
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Immunogen KLH conjugated synthetic peptide derived from human PRDX1
Isotype IgG
Purification Purified by Protein A.
Alternative Name Prdx1 (PRDX1 Antibody Abstract)
Background

Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity).

Subcellular location: Cytoplasm

Synonyms: PAG, PAGA, PAGB, PRX1, PRXI, MSP23, NKEFA, TDPX2, NKEF-A, Peroxiredoxin-1, Natural killer cell-enhancing factor A, Proliferation-associated gene protein, Thioredoxin peroxidase 2, Thioredoxin-dependent peroxide reductase 2, PRDX1

Gene ID 5052
UniProt Q06830
Pathways p53 Signaling, EGFR Signaling Pathway, CXCR4-mediated Signaling Events
Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months
Product cited in: Szabó-Taylor, Tóth, Balogh, Sódar, Kádár, Pálóczi, Fekete, Németh, Osteikoetxea, Vukman, Holub, Pállinger, Nagy, Winyard, Buzás: "Monocyte activation drives preservation of membrane thiols by promoting release of oxidised membrane moieties via extracellular vesicles." in: Free radical biology & medicine, Vol. 108, pp. 56-65, 2017 (PubMed). Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).

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