PTGER1 antibody (AA 61-160) (Alexa Fluor 647)

Catalog No. ABIN912486

Product Details anti-PTGER1 Antibody (Alexa Fluor 647)

Target: PTGER1 (Prostaglandin E Receptor 1 (Subtype EP1), 42kDa (PTGER1))

Binding Specificity: AA 61-160

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGER1 antibody is conjugated to Alexa Fluor 647

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Prostaglandin E Receptor EP1

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

References for anti-PTGER1 antibody (Alexa Fluor 647) (ABIN912486)

Li, He, Ma, Yu, Bhave, Lentz, Tan, Guzman, Zhao, Xue: "Prostaglandin E1 and Its Analog Misoprostol Inhibit Human CML Stem Cell Self-Renewal via EP4 Receptor Activation and Repression of AP-1." in: Cell stem cell, Vol. 21, Issue 3, pp. 359-373.e5, (2017) (PubMed).

Target Details for PTGER1

Target: PTGER1 (Prostaglandin E Receptor 1 (Subtype EP1), 42kDa (PTGER1))

Alternative Name: PTGER1 (PTGER1 Products)

Synonyms: EP1 antibody, PTGER1 antibody, 42kDa antibody, Ptgerep1 antibody, prostaglandin E receptor 1 antibody, prostaglandin E receptor 1 (subtype EP1), 42kDa antibody, prostaglandin E receptor 1 (subtype EP1) antibody, PTGER1 antibody, Ptger1 antibody

Background:

Synonyms: EP1, Prostaglandin E2 receptor EP1 subtype, PGE receptor EP1 subtype, PGE2 receptor EP1 subtype, Prostanoid EP1 receptor, PTGER1

Background: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues.

Gene ID: 5731

UniProt: P34995