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SART1 antibody (AA 701-800) (Alexa Fluor 350)

SART1 Reactivity: Human WB, IF (p), IF (cc) Host: Rabbit Polyclonal Alexa Fluor 350
Catalog No. ABIN914381
  • Target See all SART1 Antibodies
    SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))
    Binding Specificity
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 701-800
    Reactivity
    • 32
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 29
    • 2
    • 1
    Rabbit
    Clonality
    • 32
    Polyclonal
    Conjugate
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SART1 antibody is conjugated to Alexa Fluor 350
    Application
    • 30
    • 12
    • 12
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Predicted Reactivity
    Human,Mouse,Rat,Cow,Sheep,Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SART1
    Isotype
    IgG
    Top Product
    Discover our top product SART1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))
    Alternative Name
    SART1 (SART1 Products)
    Synonyms
    Dmel\\CG6686 antibody, SART1 antibody, MGC53679 antibody, MGC132129 antibody, zgc:91927 antibody, Ara1 antibody, HOMS1 antibody, SART1259 antibody, SNRNP110 antibody, Snu66 antibody, U5-110K antibody, CG6686 gene product from transcript CG6686-RB antibody, SART1, U4/U6.U5 tri-snRNP-associated protein 1 S homeolog antibody, SART1, U4/U6.U5 tri-snRNP-associated protein 1 antibody, squamous-cell carcinoma T-cell-recognized antigen antibody, squamous cell carcinoma antigen recognized by T cells 1 antibody, CG6686 antibody, sart1.S antibody, sart1 antibody, SART1 antibody, Sart1 antibody
    Background

    Synonyms: Ara 1, ARA1, HOMS 1, HOMS1, hSART 1, hSART1, hSnu 66, hSnu66, IgE autoantigen, MGC2038, SART 1, SART1 259, SART1259 protein, SART1800 protein, SART1259, Snu 66, Snu66, Squamous cell carcinoma antigen recognised by T cells, Squamous cell carcinoma antigen recognized by T cells 1, U4/U6.U5 tri snRNP associated 110 kDa protein, U4/U6.U5 tri snRNP associated protein, SNUT1_HUMAN.

    Background: SART1 encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation, its full length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri snRNP to the pre spliceosome in the spliceosome assembly pathway.

    Gene ID
    9092
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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