Toll-Like Receptor 11 (Tlr11) (Internal Region) antibody

Details for Product No. ABIN920621
Antigen
Epitope
Internal Region
19
3
3
3
2
2
1
1
1
Reactivity
Mouse (Murine)
38
7
4
3
3
Host
Rabbit
39
2
2
Clonality
Polyclonal
Conjugate
Un-conjugated
3
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
38
11
8
7
4
4
4
3
1
1
Options
Immunogen Antibody was raised against a peptide corresponding to 16 amino acids near the C- terminus of mouse TLR11
Specificity Recognizes TLR11
Purification Ion exchange chromatography
Antigen
Alternative Name TLR11 (Tlr11 Antibody Abstract)
Background Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria. Mice lacking TLR11 showed a much greater susceptibility to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system. Synonyms: Toll-like receptor 11
NCBI Accession NP_991388
Pathways Activation of Innate immune Response
Application Notes Western blot: Use at 0.5-2.0 myg/mL.
Restrictions For Research Use only
Format Liquid
Buffer 100 µL at 1 mg/mL of IgG polyclonal antibody in PBS and 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Supplier Images
Image no. 1 for anti-Toll-Like Receptor 11 (Tlr11) (Internal Region) antibody (ABIN920621) anti-Toll-Like Receptor 11 (Tlr11) (Internal Region) antibody (Image 1)
Image no. 2 for anti-Toll-Like Receptor 11 (Tlr11) (Internal Region) antibody (ABIN920621) anti-Toll-Like Receptor 11 (Tlr11) (Internal Region) antibody (Image 2)