MafF antibody (N-Term)

Catalog No. ABIN925912

Product Details anti-MafF Antibody

Target: MafF (MAFF) (Transcription Factor MafF (MAFF))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Drosophila melanogaster, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MafF antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine), Fruit Fly (Drosophila melanogaster), Zebrafish (Brachydanio rerio), Chicken

Immunogen: MAFF antibody was raised in rabbit using the N terminal of MAFF as the immunogen

Application Details

Application Notes: WB: 5 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

MAFF Blocking Peptide, catalog no. 33R-8927, is also available for use as a blocking control in assays to test for specificity of this MAFF antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for MafF

Target: MafF (MAFF) (Transcription Factor MafF (MAFF))

Alternative Name: MAFF (MAFF Products)

Synonyms: zgc:63868 antibody, MAFF antibody, U-MAF antibody, hMafF antibody, MAF bZIP transcription factor F antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F S homeolog antibody, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) antibody, Maff antibody, maff antibody, MAFF antibody, maff.S antibody

Background: MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. MAFF can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. MAFF may also be involved in the cellular stress response. Synonyms: Polyclonal MAFF antibody, Anti-MAFF antibody, v-maf musculoaponeurotic fibrosarcoma oncogene homolog F, avian antibody.

Pathways: Myometrial Relaxation and Contraction