NR2F2 antibody (N-Term)

Catalog No. ABIN925921

Product Details anti-NR2F2 Antibody

Target: NR2F2 (Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Chicken, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR2F2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Chicken, Zebrafish (Brachydanio rerio), Frog

Immunogen: NR2 F2 antibody was raised in rabbit using the N terminal of NR2 2 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

NR2F2 Blocking Peptide, catalog no. 33R-7495, is also available for use as a blocking control in assays to test for specificity of this NR2F2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for NR2F2

Target: NR2F2 (Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2))

Alternative Name: NR2F2 (NR2F2 Products)

Synonyms: nr2f2 antibody, MGC52954 antibody, ARP1 antibody, COUPTFB antibody, COUPTFII antibody, NF-E3 antibody, NR2F1 antibody, SVP40 antibody, TFCOUP2 antibody, 2700033K02Rik antibody, 9430015G03Rik antibody, ARP-1 antibody, Aporp1 antibody, COUP-TF2 antibody, COUP-TFII antibody, EAR3 antibody, Tcfcoup2 antibody, Tfcoup2 antibody, fc94g08 antibody, svp40 antibody, svp[40] antibody, wu:fc94g08 antibody, nuclear receptor subfamily 2 group F member 2 L homeolog antibody, Nr2f2 protein antibody, nuclear receptor subfamily 2 group F member 2 antibody, nuclear receptor subfamily 2, group F, member 2 antibody, nr2f2.L antibody, nr2f2 antibody, NR2F2 antibody, Nr2f2 antibody

Background: NR2F2, an orphan member of the nuclear hormone receptor superfamily, acts as a transcriptional repressor by antagonizing the functions of other nuclear hormone receptors and by actively silencing transcription. However, in certain contexts, NR2F2 stimulates transcription directly. NR2F2, MyoD and p300 interact in a competitive manner, and that increasing amounts of NR2F2 have the ability to reduce the interaction between myoD and p300 invitro. NR2F2 post-transcriptionally regulates myoD activity/function, and that crosstalk between orphan nuclear receptors and the myogenic bHLH proteins has functional consequences for differentiation. Synonyms: Polyclonal NR2F2 antibody, Anti-NR2F2 antibody, nuclear receptor subfamily 2, group F, member 2 antibody, ARP1 antibody, COUP-TFII antibody, COUPTFB antibody, MGC117452 antibody, SVP40 antibody, TFCOUP2 antibody.

Pathways: Steroid Hormone Mediated Signaling Pathway