GADD45A antibody (C-Term)

Catalog No. ABIN926429

Product Details anti-GADD45A Antibody

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GADD45A antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: GADD45 A antibody was raised in rabbit using the C terminal of GADD45 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

GADD45A Blocking Peptide, catalog no. 33R-5403, is also available for use as a blocking control in assays to test for specificity of this GADD45A antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for GADD45A

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Alternative Name: GADD45A (GADD45A Products)

Synonyms: MGC53491 antibody, zgc:91795 antibody, gadd45a antibody, GADD45A antibody, ddit1 antibody, gadd45 antibody, GADD45 antibody, AA545191 antibody, Ddit1 antibody, DDIT1 antibody, Gadd45 antibody, growth arrest and DNA damage inducible alpha L homeolog antibody, growth arrest and DNA-damage-inducible, alpha, b antibody, growth arrest and DNA damage inducible alpha antibody, growth arrest and DNA damage-inducible protein 45 antibody, growth arrest and DNA-damage-inducible 45 alpha antibody, growth arrest and DNA-damage-inducible, alpha antibody, gadd45a.L antibody, gadd45ab antibody, GADD45A antibody, gadd45a antibody, GADD45 antibody, Gadd45a antibody

Background: GADD45A responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of GADD45A gene is mediated by both p53-dependent and -independent mechanisms. Synonyms: Polyclonal GADD45A antibody, Anti-GADD45A antibody, growth arrest and DNA-damage-inducible, alpha antibody, DDIT1 antibody, GADD45 antibody.

Pathways: p53 Signaling, Cell Division Cycle