Cathepsin K antibody (Middle Region)

Catalog No. ABIN926630

Product Details anti-Cathepsin K Antibody

Target: Cathepsin K (CTSK)

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin K antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: CTSK antibody was raised in rabbit using the middle region of CTSK as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

CTSK Blocking Peptide, catalog no. 33R-8691, is also available for use as a blocking control in assays to test for specificity of this CTSK antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Cathepsin K

Target: Cathepsin K (CTSK)

Alternative Name: CTSK (CTSK Products)

Synonyms: CTS02 antibody, CTSO antibody, CTSO1 antibody, CTSO2 antibody, PKND antibody, PYCD antibody, AI323530 antibody, MMS10-Q antibody, Ms10q antibody, catK antibody, CTSK antibody, wu:fa95f03 antibody, wu:fb08b05 antibody, zgc:110367 antibody, cts02 antibody, ctso antibody, ctso1 antibody, ctso2 antibody, pknd antibody, pycd antibody, OC-2 antibody, catk antibody, cathepsin K antibody, cathepsin K L homeolog antibody, Cathepsin K antibody, CTSK antibody, Ctsk antibody, ctsk antibody, ctsk.L antibody, catk antibody

Background: The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. Synonyms: Polyclonal CTSK antibody, Anti-CTSK antibody, cathepsin K antibody, CTS02 antibody, CTSO antibody, CTSO1 antibody, CTSO2 antibody, MGC23107 antibody, PKND antibody, PYCD antibody.

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades