INPP5D antibody (C-Term)
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- Target See all INPP5D Antibodies
- INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This INPP5D antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Purified
- Immunogen
- INPP5 D antibody was raised in rabbit using the C terminal of INPP5 as the immunogen
- Top Product
- Discover our top product INPP5D Primary Antibody
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- Application Notes
- Optimal conditions should be determined by the investigator.
- Comment
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INPP5D Blocking Peptide, catalog no. 33R-7282, is also available for use as a blocking control in assays to test for specificity of this INPP5D antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
- Alternative Name
- INPP5D (INPP5D Products)
- Synonyms
- INPP5D antibody, 256.t00004 antibody, 13.t00027 antibody, ship antibody, ship1 antibody, AI323613 antibody, SHIP antibody, SHIP-1 antibody, SHIP1 antibody, s-SHIP antibody, SIP-145 antibody, hp51CN antibody, inositol polyphosphate-5-phosphatase D antibody, phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 antibody, inositol polyphosphate 5-phosphatase antibody, inositol polyphosphate-5-phosphatase D L homeolog antibody, INPP5D antibody, LOC100446045 antibody, inpp5d antibody, EHI_159880 antibody, EHI_153490 antibody, inpp5d.L antibody, LOC100380693 antibody, Inpp5d antibody
- Background
- This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival. Synonyms: Polyclonal INPP5D antibody, Anti-INPP5D antibody, inositol polyphosphate-5-phosphatase, 145kDa antibody, MGC104855 antibody, MGC142140 antibody, MGC142142 antibody, SHIP antibody, SHIP1 antibody, SIP-145 antibody, hp51CN antibody.
- Pathways
- TCR Signaling, BCR Signaling, Warburg Effect
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