MUS81 antibody (Middle Region)

Catalog No. ABIN926738

Product Details anti-MUS81 Antibody

Target: MUS81 (MUS81 Endonuclease Homolog (MUS81))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUS81 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: MUS81 antibody was raised in rabbit using the middle region of MUS81 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

MUS81 Blocking Peptide, catalog no. 33R-7043, is also available for use as a blocking control in assays to test for specificity of this MUS81 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for MUS81

Target: MUS81 (MUS81 Endonuclease Homolog (MUS81))

Alternative Name: MUS81 (MUS81 Products)

Background: MUS81 interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. It may be required in mitosis for the processing of stalled or collapsed replication forks. Synonyms: Polyclonal MUS81 antibody, Anti-MUS81 antibody, MUS81 endonuclease homolog, S. cerevisiae antibody, FLJ21012 antibody, FLJ44872 antibody.

Pathways: DNA Damage Repair