GIT2 antibody (C-Term)

Catalog No. ABIN926771

Product Details anti-GIT2 Antibody

Target: GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GIT2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: GIT2 antibody was raised in rabbit using the C terminal of GIT2 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

GIT2 Blocking Peptide, catalog no. 33R-9761, is also available for use as a blocking control in assays to test for specificity of this GIT2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for GIT2

Target: GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))

Alternative Name: GIT2 (GIT2 Products)

Synonyms: CAT-2 antibody, CAT2 antibody, cat-2 antibody, xgit2 antibody, git2 antibody, si:dkey-234h16.4 antibody, 1500036H07Rik antibody, 5830420E16Rik antibody, 6430510B20Rik antibody, 9630056M03Rik antibody, B230104M05Rik antibody, mKIAA0148 antibody, zgc:158416 antibody, GIT ArfGAP 2 antibody, G protein-coupled receptor kinase interacting ArfGAP 2 antibody, G protein-coupled receptor kinase interacting ArfGAP 2a antibody, G protein-coupled receptor kinase-interactor 2 antibody, G protein-coupled receptor kinase interacting ArfGAP 2 L homeolog antibody, G protein-coupled receptor kinase interacting ArfGAP 2b antibody, GIT2 antibody, git2 antibody, git2a antibody, Git2 antibody, git2.L antibody, git2b antibody

Background: This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. Synonyms: Polyclonal GIT2 antibody, Anti-GIT2 antibody, G protein-coupled receptor kinase interacting ArfGAP 2 antibody, CAT-2 antibody, DKFZp686G01261 antibody, KIAA0148 antibody, MGC760 antibody.

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling