ARFGAP3 antibody (N-Term)

Catalog No. ABIN926806

Product Details anti-ARFGAP3 Antibody

Target: ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARFGAP3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: ARFGAP3 antibody was raised in rabbit using the N terminal of ARFGAP3 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

ARFGAP3 Blocking Peptide, catalog no. 33R-10325, is also available for use as a blocking control in assays to test for specificity of this ARFGAP3 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for ARFGAP3

Target: ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))

Alternative Name: ARFGAP3 (ARFGAP3 Products)

Synonyms: ARFGAP1 antibody, 0610009H19Rik antibody, 1810004P07Rik antibody, 1810035F16Rik antibody, 9130416J18Rik antibody, Arfgap1 antibody, arfgap1 antibody, xgap antibody, zgc:85765 antibody, arfgap3 antibody, ADP ribosylation factor GTPase activating protein 3 antibody, ADP-ribosylation factor GTPase activating protein 3 antibody, ADP ribosylation factor GTPase activating protein 3 S homeolog antibody, ARFGAP3 antibody, Arfgap3 antibody, arfgap3 antibody, arfgap3.S antibody

Background: The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. Synonyms: Polyclonal ARFGAP3 antibody, Anti-ARFGAP3 antibody, ADP-ribosylation factor GTPase activating protein 3 antibody, ARFGAP1 antibody, FLJ45618 antibody.