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CHRNB3 antibody (Middle Region)

CHRNB3 Reactivity: Human, Mouse, Rat, Dog, Chicken, Xenopus laevis WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN926966
  • Target See all CHRNB3 Antibodies
    CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))
    Binding Specificity
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 26
    • 13
    • 13
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Chicken, Xenopus laevis
    Host
    • 24
    • 3
    • 1
    Rabbit
    Clonality
    • 25
    • 3
    Polyclonal
    Conjugate
    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHRNB3 antibody is un-conjugated
    Application
    • 16
    • 12
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Mouse (Murine), Rat (Rattus), Dog (Canine), Chicken, Frog
    Purification
    Purified
    Immunogen
    CHRNB3 antibody was raised in rabbit using the middle region of CHRNB3 as the immunogen
    Top Product
    Discover our top product CHRNB3 Primary Antibody
  • Application Notes
    WB: 0.03 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    CHRNB3 Blocking Peptide, catalog no. 33R-10069, is also available for use as a blocking control in assays to test for specificity of this CHRNB3 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Concentration
    Lot specific
    Buffer
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • Target
    CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))
    Alternative Name
    CHRNB3 (CHRNB3 Products)
    Synonyms
    5730417K16Rik antibody, Acrb3 antibody, NACHR antibody, CHRNB3 antibody, chrnb3 antibody, cholinergic receptor nicotinic beta 3 subunit antibody, neuronal acetylcholine receptor subunit beta-3 antibody, cholinergic receptor, nicotinic, beta polypeptide 3 antibody, cholinergic receptor, nicotinic beta 3 L homeolog antibody, cholinergic receptor, nicotinic beta 3 antibody, cholinergic receptor, nicotinic, beta 3b (neuronal) antibody, cholinergic receptor, nicotinic, beta polypeptide 3a antibody, CHRNB3 antibody, CpipJ_CPIJ012638 antibody, Chrnb3 antibody, chrnb3.L antibody, chrnb3 antibody, chrnb3b antibody, chrnb3a antibody
    Background
    Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels nAChRs are pentameric structures that are made up of combinations of individual subunits. CHRNB3 is one of the subunits of nAChR. Twelve neuronal nAChR subunits have been described, alpha2-alpha10 and beta2-beta4. CHRNB3 decreased the channel mean open time and burst length. There was also an increase in single channel slope conductance. On the other hand, the calcium permeability and the pharmacological properties of beta3-containing receptors differed little from those of without beta3. Dysfunction of nAChR has been linked to a number of human diseases such as schizophrenia, Alzheimer's and Parkinson's diseases. nAChRs also play a significant role in nicotine addiction. Synonyms: Polyclonal CHRNB3 antibody, Anti-CHRNB3 antibody, cholinergic receptor, nicotinic, beta 3 antibody.
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