TLE1 antibody (N-Term)

Catalog No. ABIN927372

Product Details anti-TLE1 Antibody

Target: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Binding Specificity: N-Term

Reactivity: Human, Zebrafish (Danio rerio), Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLE1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Chicken, Zebrafish (Brachydanio rerio)

Purification: Purified

Immunogen: TLE1 antibody was raised in rabbit using the N terminal of TLE1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

TLE1 Blocking Peptide, catalog no. 33R-8077, is also available for use as a blocking control in assays to test for specificity of this TLE1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for TLE1

Target: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Alternative Name: TLE1 (TLE1 Products)

Background: TLE1 is a transcriptional corepressor that binds to a number of transcription factors. TLE1 inhibits NF-kappa-B-regulated gene expression and the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. TLE1 has an unusual function as coactivator for ESRRG. Synonyms: Polyclonal TLE1 antibody, Anti-TLE1 antibody, transducin-like enhancer of split 1, E, sp1 homolog, Drosophila antibody, ESG antibody, ESG1 antibody, GRG1 antibody.

Pathways: WNT Signaling, SARS-CoV-2 Protein Interactome