SPIC antibody (Middle Region)

Catalog No. ABIN927879

Product Details anti-SPIC Antibody

Target: SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))

Binding Specificity: Middle Region

Reactivity: Human, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPIC antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Cow (Bovine)

Purification: Purified

Immunogen: SPIC antibody was raised in rabbit using the middle region of SPIC as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

SPIC Blocking Peptide, catalog no. 33R-5334, is also available for use as a blocking control in assays to test for specificity of this SPIC antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for SPIC

Target: SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))

Alternative Name: SPIC (SPIC Products)

Synonyms: SPI-C antibody, AU019198 antibody, C76795 antibody, Prf antibody, Spi-C antibody, zgc:101790 antibody, spi-c antibody, spic antibody, Spi-C transcription factor antibody, transcription factor Spi-C-like antibody, Spi-C transcription factor (Spi-1/PU.1 related) antibody, Spi-C transcription factor (Spi-1/PU.1 related) S homeolog antibody, SPIC antibody, LOC100349167 antibody, Spic antibody, spic antibody, spic.S antibody

Background: SPIC controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. SPIC is a transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. SPIC regulates VCAM1 gene expression. Synonyms: Polyclonal SPIC antibody, Anti-SPIC antibody, Spi-C transcription factor, Spi-1/PU.1 related antibody, MGC40611 antibody, SPI-C antibody.