OAS1 antibody (Middle Region)
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- Target See all OAS1 Antibodies
- OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Pig, Cow, Dog, Chicken
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This OAS1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Rat (Rattus), Mouse (Murine), Cow (Bovine), Dog (Canine), Pig (Porcine), Chicken
- Purification
- Purified
- Immunogen
- OAS1 antibody was raised in rabbit using the middle region of OAS1 as the immunogen
- Top Product
- Discover our top product OAS1 Primary Antibody
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- Application Notes
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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OAS1 Blocking Peptide, catalog no. 33R-8155, is also available for use as a blocking control in assays to test for specificity of this OAS1 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
- Alternative Name
- OAS1 (OAS1 Products)
- Synonyms
- OAS1 antibody, IFI-4 antibody, OIAS antibody, OIASI antibody, L3 antibody, Pp2a2 antibody, 2',5'-oligoadenylate synthetase 1 antibody, 2'-5'-oligoadenylate synthetase 1 antibody, 2'-5' oligoadenylate synthetase 1A antibody, protein phosphatase 2 catalytic subunit beta antibody, OAS1 antibody, Oas1a antibody, Ppp2cb antibody, Oas1 antibody
- Background
- This protein is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Synonyms: Polyclonal OAS1 antibody, Anti-OAS1 antibody, 2',5'-oligoadenylate synthetase 1, 40/46kDa antibody, IFI-4 antibody, OIAS antibody, OIASI antibody.
- Pathways
- Hepatitis C
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