PPP2R2D antibody (C-Term)

Catalog No. ABIN928830

Product Details anti-PPP2R2D Antibody

Target: PPP2R2D (Protein Phosphatase 2, Regulatory Subunit B, delta (PPP2R2D))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R2D antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine)

Purification: Purified

Immunogen: Ppp2 r2 antibody was raised in rabbit using the C terminal of Ppp2 2 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

Ppp2r2d Blocking Peptide, catalog no. 33R-8132, is also available for use as a blocking control in assays to test for specificity of this Ppp2r2d antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for PPP2R2D

Target: PPP2R2D (Protein Phosphatase 2, Regulatory Subunit B, delta (PPP2R2D))

Alternative Name: Ppp2r2d (PPP2R2D Products)

Synonyms: 1300017E19Rik antibody, D7Ertd753e antibody, MDS026 antibody, protein phosphatase 2, regulatory subunit B, delta antibody, protein phosphatase 2 regulatory subunit Bdelta antibody, protein phosphatase 2 regulatory subunit B, delta S homeolog antibody, Ppp2r2d antibody, PPP2R2D antibody, ppp2r2d.S antibody

Background: Ppp2r2d is a B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment. Synonyms: Polyclonal Ppp2r2d antibody, Anti-Ppp2r2d antibody, protein phosphatase 2, regulatory subunit B, delta isoform antibody, 1300017E19Rik antibody, D7Ertd753e antibody, MDS026 antibody.