PSMD3 antibody (Middle Region)

Catalog No. ABIN928856

Product Details anti-PSMD3 Antibody

Target: PSMD3 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 3 (PSMD3))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: PSMD3 antibody was raised in rabbit using the middle region of PSMD3 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

PSMD3 Blocking Peptide, catalog no. 33R-10253, is also available for use as a blocking control in assays to test for specificity of this PSMD3 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for PSMD3

Target: PSMD3 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 3 (PSMD3))

Alternative Name: PSMD3 (PSMD3 Products)

Synonyms: P58 antibody, RPN3 antibody, S3 antibody, TSTA2 antibody, AI255837 antibody, AntP91a antibody, D11Bwg1349e antibody, Psd3 antibody, Tstap91a antibody, proteasome 26S subunit, non-ATPase 3 antibody, proteasome 26S subunit, non-ATPase 3 S homeolog antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 antibody, 26S proteasome non-ATPase regulatory subunit 3 antibody, PSMD3 antibody, psmd3.S antibody, Psmd3 antibody, rpn-3 antibody

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Synonyms: Polyclonal PSMD3 antibody, Anti-PSMD3 antibody, proteasome, prosome, macropain 26S subunit, non-ATPase, 3 antibody, P58 antibody, RPN3 antibody, S3 antibody.

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway