CYP8B1 antibody (Middle Region)

Catalog No. ABIN929451

Product Details anti-CYP8B1 Antibody

Target: CYP8B1 (Cytochrome P450, Family 8, Subfamily B, Polypeptide 1 (CYP8B1))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP8B1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: CYP8 B1 antibody was raised in rabbit using the middle region of CYP8 1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

CYP8B1 Blocking Peptide, catalog no. 33R-8610, is also available for use as a blocking control in assays to test for specificity of this CYP8B1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for CYP8B1

Target: CYP8B1 (Cytochrome P450, Family 8, Subfamily B, Polypeptide 1 (CYP8B1))

Alternative Name: CYP8B1 (CYP8B1 Products)

Synonyms: MGC64456 antibody, CYP8B antibody, CP8B antibody, CYP12 antibody, cytochrome P450 family 8 subfamily B member 1 antibody, cytochrome P450 family 8 subfamily B member 1 S homeolog antibody, cytochrome P450, family 8, subfamily B, polypeptide 1 antibody, cytochrome P450, family 8, subfamily b, polypeptide 1 antibody, Cyp8b1 antibody, cyp8b1.S antibody, CYP8B1 antibody

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the cytochrome P450 genes in that it is intronless. Synonyms: Polyclonal CYP8B1 antibody, Anti-CYP8B1 antibody, cytochrome P450, family 8, subfamily B, polypeptide 1 antibody, CP8B antibody, CYP12 antibody, FLJ17826 antibody.