CYP11B1 antibody (Middle Region)

Catalog No. ABIN929453

Product Details anti-CYP11B1 Antibody

Target: CYP11B1 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 1 (CYP11B1))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP11B1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: CYP11 B1 antibody was raised in rabbit using the middle region of CYP11 1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

CYP11B1 Blocking Peptide, catalog no. 33R-4783, is also available for use as a blocking control in assays to test for specificity of this CYP11B1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for CYP11B1

Target: CYP11B1 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 1 (CYP11B1))

Alternative Name: CYP11B1 (CYP11B1 Products)

Synonyms: CPN1 antibody, CYP11B antibody, FHI antibody, P450C11 antibody, AA389061 antibody, Cyp11b antibody, Cyp11b-1 antibody, Cp11ba antibody, RATCP11BA antibody, P450c11 antibody, cytochrome P450, family 11, subfamily B, polypeptide 1 antibody, cytochrome P450 family 11 subfamily B member 1 antibody, cytochrome P450, family 11, subfamily b, polypeptide 1 antibody, cytochrome P450, subfamily XI B, polypeptide 1 antibody, CYP11B1 antibody, Cyp11b1 antibody

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. Synonyms: Polyclonal CYP11B1 antibody, Anti-CYP11B1 antibody, cytochrome P450, family 11, subfamily B, polypeptide 1 antibody, CPN1 antibody, CYP11B antibody, DKFZp686B05283 antibody, FHI antibody, FLJ36771 antibody, P450C11 antibody.

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis