Core-Binding Factor, beta Subunit (CBFB) antibody

Details for Product No. ABIN931127, Supplier: Log in to see
Antigen
  • PEBP2B
  • Cbfb
  • pebp2b
  • Pebp2
  • CBFB
  • unp1266
  • cbf-beta
  • cbfbeta
  • pea2-beta
  • pebp2-beta
  • AI893578
  • PEA2
  • PEBP2b
  • Pebpb2
  • core-binding factor beta subunit
  • core binding factor beta subunit
  • core-binding factor, beta subunit
  • core-binding factor, beta subunit S homeolog
  • core binding factor beta
  • CBFB
  • Cbfb
  • cbfb
  • cbfb.S
Alternatives
anti-Chicken Core-Binding Factor, beta Subunit antibody for Western Blotting
Reactivity
Human
94
35
22
5
4
4
4
4
4
2
2
1
1
1
Host
Mouse
76
13
6
2
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
4
4
4
3
3
3
Application
Dot Blot (DB), Immunocytochemistry (ICC), Western Blotting (WB)
79
60
35
17
11
7
6
6
4
4
3
2
1
1
1
Options
Supplier
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Immunogen CBFB antibody was raised in mouse using recombinant Human Core-Binding Factor, Beta Subunit
Clone 344C3a
Isotype IgG1
Cross-Reactivity Human
Cross-Reactivity (Details) Other species not studied.
Purification Protein G affinity chromatography
Antigen
Alternative Name CBFB (CBFB Antibody Abstract)
Background The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit, it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters. Synonyms: Monoclonal CBFB antibody, Anti-CBFB antibody, Core-binding factor subunit beta antibody, PEBP2B antibody.
Pathways Regulation of Lipid Metabolism by PPARalpha
Application Notes WB: 0.2-2 µg/mL
Optimal conditions should be determined by the investigator.
Restrictions For Research Use only
Concentration Lot specific
Buffer CBFB antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
Preservative Sodium azide
Precaution of Use This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
Storage 4 °C
Storage Comment Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
Supplier Images
Immunofluorescence (IF) image for anti-Core-Binding Factor, beta Subunit (CBFB) antibody (ABIN931127) Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde...
Western Blotting (WB) image for anti-Core-Binding Factor, beta Subunit (CBFB) antibody (ABIN931127) anti-Core-Binding Factor, beta Subunit (CBFB) antibody (Image 2)
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