IGF1R antibody

Catalog No. ABIN932245

Product Details anti-IGF1R Antibody

Target: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IGF1R antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: IGF1 R antibody was raised in Mouse using a purified recombinant fragment of IGF1 expressed in E. coli as the immunogen.

Clone: 3G5C1

Isotype: IgG2a

Application Details

Application Notes: ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for IGF1R

Target: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Alternative Name: IGF1R (IGF1R Products)

Synonyms: CMT2N antibody, CD221 antibody, IGFIR antibody, IGFR antibody, JTK13 antibody, IGFIRC antibody, IGFR1 antibody, IGF-1R antibody, IGF1R antibody, DKFZp469I0618 antibody, igf-1r antibody, xIGF-1R antibody, xIGFR antibody, xigf1r antibody, A330103N21Rik antibody, D930020L01 antibody, hyft antibody, igf-ir antibody, IGF-IR antibody, IGF-IRb antibody, wu:fb03h06 antibody, IGF-IRa antibody, sb:eu1090 antibody, wu:fi20b10 antibody, alanyl-tRNA synthetase antibody, insulin like growth factor 1 receptor antibody, insulin-like growth factor 1 receptor antibody, insulin-like growth factor 1 antibody, insulin-like growth factor I receptor antibody, insulin like growth factor 1 receptor S homeolog antibody, insulin-like growth factor 1b receptor antibody, insulin-like growth factor 1a receptor antibody, AARS antibody, IGF1R antibody, Igf1r antibody, igf1r antibody, Igf1 antibody, LOC780503 antibody, LOC100136427 antibody, igf1r.S antibody, igf1rb antibody, igf1ra antibody

Background: IGF1R binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-likegrowth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha andbeta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent byenhancing cell survival. Synonyms: Monoclonal IGF1R antibody, Anti-IGF1R antibody, Insulin-like growth factor 1 receptor antibody, CD221 antibody, JTK13 antibody, IGF-I receptor antibody, IGF I receptor antibody, CD221 antigen antibody.

Pathways: RTK Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy