IL1RN antibody

Catalog No. ABIN933583

Product Details anti-IL1RN Antibody

Target: IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL1RN antibody is un-conjugated

Application: ELISA

Purification: Protein A affinity chromatography

Immunogen: IL-1 ra antibody was raised in Mouse using recombinant human IL-1 a as the immunogen.

Clone: KT6

Isotype: IgG1

Application Details

Application Notes: ELISA: 1 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Supplied in PBS containing 0.1 % sodium azide as a preservative

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C/-80 °C

Storage Comment: Store at 4 °C for up to 1 month. For long term storage, aliquot and store at -20 to -80 °C.

Target Details for IL1RN

Target: IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))

Alternative Name: IL1RA (IL1RN Products)

Synonyms: DIRA antibody, ICIL-1RA antibody, IL-1RN antibody, IL-1ra antibody, IL-1ra3 antibody, IL1F3 antibody, IL1RA antibody, IRAP antibody, MVCD4 antibody, IRAP1 antibody, IL1RN antibody, IL-1RA antibody, F630041P17Rik antibody, interleukin 1 receptor antagonist antibody, interleukin 1 receptor antagonist-like antibody, IL1RN antibody, Il1rn antibody, IL1RNL antibody

Background: IL1RA is a naturally occurring inflammatory inhibitor protein. It inhibits the activity of IL1a and IL1beta by competitively blocking binding to their type I and type II receptors. IL1Ra is produced by corneal epithelial cells, monocytes, neutrophils, macrophages, and fibroblasts. Therapeutically, IL1Ra may help in the treatment of sepsis, cachexia, rheumatoid arthritis, chronic myelogenous leukemia, asthma, psoriasis, and inflammatory bowel disease. Synonyms: Monoclonal IL1RA antibody, Anti-IL1RA antibody, IL1 RA antibody, IL1-RA antibody, Interleukin 1 receptor antagonist antibody.

Pathways: NF-kappaB Signaling, Hormone Transport, Cancer Immune Checkpoints