MUC1 antibody

Catalog No. ABIN933960

Product Details anti-MUC1 Antibody

Target: MUC1 (Mucin 1 (MUC1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MUC1 antibody is un-conjugated

Application: ELISA, Immunoassay (IA)

Cross-Reactivity (Details): Minimal cross-reactivity with human CA125

Purification: Protein G affinity chromatography

Immunogen: CA 15-3 antibody was raised in mouse using human CA 15-3 antigen from a human cell line as the immunogen.

Clone: M2012112

Isotype: IgG2b

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Comment:

This antibody can be used as the detection when paired with CA 15-3 antibody, Cat. No. 10-CA15A as solid phase coating antibody or with CA 15-3 antibody, Cat. No. 10-CA15C. It can also be paired with 61-CA15HRP as a HRP conjugated detection antibody.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: PBS buffer, pH 7.4 with 0.1 % Na Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: DO NOT FREEZE.
Dilute only prior to immediate use.

Storage: 4 °C

Target Details for MUC1

Target: MUC1 (Mucin 1 (MUC1))

Alternative Name: CA 15-3 (MUC1 Products)

Synonyms: CA 15-3 antibody, CD227 antibody, EMA antibody, H23AG antibody, KL-6 antibody, MAM6 antibody, MCKD1 antibody, MUC-1 antibody, MUC-1/SEC antibody, MUC-1/X antibody, MUC1/ZD antibody, PEM antibody, PEMT antibody, PUM antibody, Muc-1 antibody, mucin 1, cell surface associated antibody, mucin 1, transmembrane antibody, MUC1 antibody, Muc1 antibody

Background: CA 15-3 is breast tumor marker. Diagnostic tests measuring the MUC1- glycoprotein are FDA/EU approved including CA 15-3, CA 27-29 and Br assays. Reoccurrence detection of breast cancer by MUC-1 assay can preceed confirmation by radiological detection methods by 1-9 months. Synonyms: Monoclonal CA 15-3 antibody, Anti-CA 15-3 antibody, Cancer Antigen 15-3 antibody, CA 15-3 antibody, Breast Tumor antibody.

Pathways: Negative Regulation of intrinsic apoptotic Signaling