alpha 1 Microglobulin/bikunin (AMBP) (N-Term) antibody

Details for Product No. ABIN93520
Antigen
Epitope
N-Term
14
10
9
8
8
7
6
3
3
2
2
2
2
2
2
1
1
1
1
Reactivity
Rat (Rattus)
158
44
36
5
5
5
4
3
3
1
1
1
1
1
Host
Rabbit
135
42
15
1
Clonality
Polyclonal
Conjugate
Un-conjugated
21
16
13
3
3
2
2
2
2
2
2
2
1
Application
Immunocytochemistry (ICC), Radioimmunoassay (RIA), Western Blotting (WB)
137
107
71
23
15
11
10
7
6
6
4
3
3
1
1
Options
Immunogen rat alpha-1-microglobulin, full length, recombinant protein, overexpressed in baculovirus-infected insect cells with N-terminal His-tag
Cross-Reactivity (Details) Not reactive in: no confirmed exceptions from predicted reactivity known in the moment
Predicted Reactivity mouse
Characteristics Expected / apparent Molecular Weight of the Antigene: 27 kDa
Purification serum
Antigen
Alternative Name AMBP (AMBP Antibody Abstract)
Background Alpha-1-microglobulin is a 27-kDa glycoprotein with immunosuppressive properties. A gene AMBP in the lipocalin cluster encodes alpha-1-microglobulin together with a Kunitz-type proteinase inhibitor, bikunin. The gene is translated into the alpha-1-microglobulin-bikunin precursor, which is subsequently cleaved and the two proteins are secreted to the blood separately. Alpha-1-microglobulin is found in blood and in connective tissue in most organs. It is most abundant at interfaces between the cells of the body and the environment, such as in lungs, intestine, kidneys and placenta. Alpha 1-microglobulin is an immunomodulatory protein with a broad spectrum of possible clinical applications and seems a promising marker for evaluation of tubular function.
Molecular Weight 27 kDa
Application Notes 1: 2000 (WB), 1: 6000 (RIA), 1: 5000 (ELISA), 1: 200 (IHC)
Restrictions For Research Use only
Format Lyophilized
Reconstitution For reconstitution add 200 μL of sterile water
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
Once reconstituted make aliquots to avoid repreated freeze-thaw cycles.
Storage -20 °C
Storage Comment store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.