Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4) antibody

Details for Product No. ABIN93526
Antigen
Reactivity
Human
82
32
32
8
8
8
8
7
7
7
6
5
5
3
3
2
Host
Rabbit
73
9
2
1
Clonality
Polyclonal
Conjugate
Un-conjugated
5
4
4
4
4
4
1
1
1
1
1
1
Application
Western Blotting (WB)
80
45
30
7
4
3
2
1
1
1
1
1
Options
Immunogen Recombinant human S5a Proteasome subunit also known as Rpn10 P55036
Cross-Reactivity (Details) No cross-reactivity with: Drosophila melanogaster
Characteristics Expected / apparent Molecular Weight of the Antigene: 40 kDa
Purification serum
Antigen
Alternative Name S5a (Psmd4 Antibody Abstract)
Background Proteasome-dependent degradation serves an essential role in the removal of a wide variety of key nuclear and cytosolic proteins. Substrates are targeted for proteolysis by the ubiquitin pathway before being degraded by the 26 S proteasome. The subunit of the proteasome, S5a, was identified to bind to polyubiquitin in vitro and thus proposed to act as a substrate recognition component. Alternative names: 26S proteasome non-ATPase regulatory subunit 4, Rpn10, multiubiquitin chain-binding protein, antisecretory factor 1, ASF, AF
Molecular Weight 40 kDa
UniProt P55036
Pathways Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
Application Notes 1:2000 (WB)
Restrictions For Research Use only
Format Lyophilized
Reconstitution For reconstitution add 100 μL of sterile water.
Handling Advice Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
Once reconstituted make aliquots to avoid repreated freeze-thaw cycles.
Storage -20 °C
Storage Comment store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.