TNFRSF21 antibody (Tumor Necrosis Factor Receptor Superfamily, Member 21) (AA 42-335)

Details for Product anti-TNFRSF21 Antibody No. ABIN94305
Antigen
Epitope
AA 42-335
11
10
10
9
9
8
8
7
7
7
4
4
4
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
143
21
17
1
1
1
1
Host
Mouse
99
48
5
Clonality (Clone)
Monoclonal ()
Conjugate
This TNFRSF21 antibody is un-conjugated
10
4
4
2
2
2
2
2
2
2
2
2
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunoprecipitation (IP)
86
67
20
20
12
9
3
2
2
2
1
Options
Immunogen A fusion protein representing amino acids 42-335 (extracellular part) of human DR6 linked to the Fc portion of human IgG1 was used as an immunogen.
Clone DR-6-04-EC
Isotype IgG1
Specificity The antibody DR-6-04-EC recognizes human DR6 (Death receptor-6), a type I transmembrane protein containing cytoplasmic death domain, widely expressed in most human tissues and cell lines.
HLDA 9 workshop
Cross-Reactivity (Details) Human
Purification Purified by protein-A affinity chromatography
Purity > 95 % (by SDS-PAGE)
Antigen
Alternative Name CD358 / DR6 (TNFRSF21 Antibody Abstract)
Background CD358 / DR6 (Death Receptor-6) is a type I transmembrane protein of the TNF receptor superfamily, expressed in most human tissues and able of inducing apoptosis through its cytoplasmic death domain. Unlike TNFR1 and Fas, DR6 induces apoptosis independently of FADD adaptor. In immune system, DR6 serves as an important regulator for CD4+ T cell proliferation and Th differentiation, and provides also a regulatory mechanism for B cell activation and humoral immune responses.
Pathways Regulation of Lipid Metabolism by PPARalpha
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Supplier Images
Image no. 1 for anti-Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 42-335) antibody (ABIN94305) Flow Cytometry analysis