CA 19-9 antibody

Catalog No. ABIN94463

Product Details anti-CA 19-9 Antibody

Target: CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CA 19-9 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: The antibody 121SLE recognizes Sialyl Lewis a-containing glycolipids (extracellular plasma membrane leaflet antigens).

Cross-Reactivity (Details): Other not tested, Human

Purification: Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).

Purity: > 95 % (by SDS-PAGE)

Immunogen: Immunoprecipitate obtained after immunodiffusion of MAb 19-9 and mucins isolated from an ovarian cyst of a 0Le(a+b-) patient.

Clone: 121SLE

Isotype: IgM

Application Details

Application Notes: Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/mL, positive control: colorectal adenocarcinoma, heat mediated antigen retrieval (sodium citrate), mAb incubation 1 hour / RT, detection DAB.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

References for anti-CA 19-9 antibody (ABIN94463)

Rye, Bovin, Vlasova, Molodyk, Baryshnikov, Kreutz, Garinther, Schultes, Noujaim, Madiyalakan, Magnani, Nilsson, Nilsson, Nustad, Norum, Bell, Cao, Suresh, Very, Freeman, Yeung, Hilgers: "Summary report on the ISOBM TD-6 workshop: analysis of 20 monoclonal antibodies against Sialyl Lewisa and related antigens. Montreux, Switzerland, September 19-24, 1997." in: Tumour biology, Vol. 19, Issue 5, pp. 390-420, (1998) (PubMed).

Target Details for CA 19-9

Target: CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))

Alternative Name: Sialyl Lewis a (CA 19-9 Products)

Background: CA-19.9