AP2B1 antibody (Middle Region)

Catalog No. ABIN950446

Product Details anti-AP2B1 Antibody

Target: AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))

Binding Specificity: AA 516-546, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP2B1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to AP2 complex subunit beta-1.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 516-546 amino acids from the Central region of human AP2B1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for AP2B1

Target: AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))

Abstract: AP2B1 Products

Synonyms: 5-HT(2B) antibody, 5-HT2B antibody, ADTB2 antibody, AP105B antibody, AP2-BETA antibody, CLAPB1 antibody, 1300012O03Rik antibody, AI788979 antibody, fa16e07 antibody, wu:fa16c06 antibody, wu:fa16e07 antibody, wu:fc18c08 antibody, zgc:55659 antibody, 5-hydroxytryptamine receptor 2B antibody, adaptor related protein complex 2 beta 1 subunit antibody, adaptor-related protein complex 2, beta 1 subunit antibody, adaptor related protein complex 2 beta 1 subunit L homeolog antibody, HTR2B antibody, AP2B1 antibody, Ap2b1 antibody, ap2b1 antibody, ap2b1.L antibody

Background: The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene.Synonyms: ADTB2, AP105B, AP2B1, Adapter-related protein complex 2 beta-1 subunit, Beta adaptin, Beta2-adaptin, CLAPB1, Clathrin assembly protein complex 2 beta large chain, Plasma membrane adaptor HA2/AP2 adaptin beta subunit

Gene ID: 163

NCBI Accession: NP_001025177

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation