CRHBP antibody (N-Term)

Catalog No. ABIN951702

Product Details anti-CRHBP Antibody

Target: CRHBP (Corticotropin Releasing Hormone Binding Protein (CRHBP))

Binding Specificity: AA 6-36, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRHBP antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to human CRHBP.

Purification: Saturated Ammonium Sulfate (SAS) precipitation

Immunogen: KLH conjugated synthetic peptide between 6-36 amino acids from the N-terminal region of human CRHBP

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CRHBP

Target: CRHBP (Corticotropin Releasing Hormone Binding Protein (CRHBP))

Alternative Name: CRHBP (CRHBP Products)

Synonyms: crh-BP antibody, GB14094 antibody, zgc:91905 antibody, CRHBP antibody, CRH-BP antibody, CRF-BP antibody, CRFBP antibody, Crfbp antibody, crhbp-A antibody, gene E antibody, corticotropin releasing hormone binding protein antibody, corticotropin releasing hormone binding protein S homeolog antibody, CRHBP antibody, crhbp antibody, crh-BP antibody, Crhbp antibody, crhbp.S antibody

Background: Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy.Synonyms: CRF-BP, CRF-binding protein, CRFBP, Corticotropin-releasing factor-binding protein, Corticotropin-releasing hormone-binding protein

Molecular Weight: 36144 Da

Gene ID: 1393

NCBI Accession: NP_001873

Pathways: Negative Regulation of Hormone Secretion