ANAPC10 antibody (Anaphase Promoting Complex Subunit 10)

Details for Product anti-ANAPC10 Antibody No. ABIN95220
Antigen
Reactivity
Human
70
34
28
2
2
2
2
2
1
1
1
1
1
1
Host
Rabbit
60
11
Clonality
Polyclonal
Conjugate
This ANAPC10 antibody is un-conjugated
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
48
25
24
13
9
7
5
4
4
3
1
1
Options
Immunogen This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the amino terminus of human APC10.
Isotype IgG
Characteristics Concentration Definition: by UV absorbance at 280 nm
Purification Antiserum
Antigen
Alternative Name APC10 (ANAPC10 Antibody Abstract)
Background APC (Anaphase-Promoting Complex or Cyclosome) is a ubiquitin ligase which specifically targets mitotic regulatory factors such as Pds1/Cut2 and cyclin B.  It was found that APC10/Doc1 is localized in centrosomes and mitotic spindles throughout mitosis, while it is also localized in kinetochores from prophase to anaphase and in mid-body in telophase and cytokinesis.  These results strongly support the notion that human APC10/Doc1 may be one of the APC core subunits rather than the transiently associated regulatory factor.
Synonyms: APC, Anaphase-Promoting Complex, Cyclosome anaphase-promoting complex subunit 10
Gene ID 10393, 150170706
UniProt Q9UM13
Pathways M Phase
Application Notes This affinity purified antibody has been tested for use in ELISA against the immunizing peptide and by western blotting against various cell lysates.  Reactivity in other immunoassays is unknown.
Restrictions For Research Use only
Format Liquid
Concentration 1.50 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Supplier Images
Image no. 1 for anti-Anaphase Promoting Complex Subunit 10 (ANAPC10) antibody (ABIN95220) Affinity Purified Rabbit anti-APC10 was used at a 1:500 dilution to detect human APC1...
Image no. 2 for anti-Anaphase Promoting Complex Subunit 10 (ANAPC10) antibody (ABIN95220) Affinity Purified Rabbit anti-APC10 was used at a 1:500 dilution to detect human APC1...