GCNT2 antibody (C-Term)

Catalog No. ABIN952480

Product Details anti-GCNT2 Antibody

Target: GCNT2 (Glucosaminyl (N-Acetyl) Transferase 2, I-Branching Enzyme (I Blood Group) (GCNT2))

Binding Specificity: AA 371-399, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCNT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human and Mouse GCNT2 / NACGT1 (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: conjugated synthetic peptide between 371-399 amino acids from the C-terminal region of Human GCNT2 / NACGT1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GCNT2

Target: GCNT2 (Glucosaminyl (N-Acetyl) Transferase 2, I-Branching Enzyme (I Blood Group) (GCNT2))

Alternative Name: GCNT2 / NACGT1 (GCNT2 Products)

Synonyms: 5330430K10Rik antibody, IGnT antibody, IGnTA antibody, IGnTB antibody, IGnTC antibody, Ignt antibody, CCAT antibody, CTRCT13 antibody, GCNT2C antibody, GCNT5 antibody, IGNT antibody, II antibody, NACGT1 antibody, NAGCT1 antibody, ULG3 antibody, bA360O19.2 antibody, bA421M1.1 antibody, glucosaminyl (N-acetyl) transferase 2, I-branching enzyme antibody, glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) antibody, Gcnt2 antibody, GCNT2 antibody

Background: This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.Synonyms: 6-N-acetylglucosaminyl-transferase, GCNT5, I-branching enzyme, IGNT, N-acetylglucosaminyltransferase, N-acetyllactosaminide beta-1

Molecular Weight: 45855 Da

Gene ID: 2651

NCBI Accession: NP_001482

Pathways: Glycosaminoglycan Metabolic Process