GPKOW antibody (Middle Region)

Catalog No. ABIN952585

Product Details anti-GPKOW Antibody

Target: GPKOW (G Patch Domain and KOW Motifs (GPKOW))

Binding Specificity: AA 308-338, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPKOW antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to GPKOW.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 308-338 amino acids from the Central region of human GPKOW

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GPKOW

Target: GPKOW (G Patch Domain and KOW Motifs (GPKOW))

Alternative Name: GPATCH5 / GPKOW (GPKOW Products)

Background: T54, also known as GPKOW (G patch domain and KOW motifs), GPATC5 or GPATCH5 (G patch domain-containing protein 5), is a potential RNA-binding protein consisting of one central G patch domain and two C-terminal KOW domains. T54 is a 476 amino acid protein belonging to the MOS2 family. It is a mammalian homolog of the Arabidopsis thaliana MOS2 (modifier of SNC1, 2) nuclear protein that is required for innate immunity. Similar to A. thaliana MOS2, T54 localizes to the nucleus and contains G patch and KOW domains, suggesting that T54 may play a similar role in mammalian innate immunity.Synonyms: G patch domain and KOW motifs-containing protein, G patch domain-containing protein 5, GPATC5, Protein MOS2 homolog, T54

Molecular Weight: 52229 Da

Gene ID: 27238

NCBI Accession: NP_056513