H2BFWT antibody (Middle Region)

Catalog No. ABIN952668

Product Details anti-H2BFWT Antibody

Target: H2BFWT (H2B Histone Family, Member W, Testis-Specific (H2BFWT))

Binding Specificity: AA 60-88, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2BFWT antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 60-88 amino acids from the Central region of Human H2BFWT

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for H2BFWT

Target: H2BFWT (H2B Histone Family, Member W, Testis-Specific (H2BFWT))

Alternative Name: H2BFWT (H2BFWT Products)

Synonyms: H2B histone family member W, testis specific antibody, H2BFWT antibody

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the H2B histone family that is specifically expressed in sperm nuclei. A polymorphism in the 5' UTR of this gene is associated with male infertility.Synonyms: H2B histone family member W testis-specific, Histone H2B type W-T

Molecular Weight: 19618 Da

Gene ID: 158983

NCBI Accession: NP_001002916