LZTS1 antibody (N-Term)

Catalog No. ABIN953266

Product Details anti-LZTS1 Antibody

Target: LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))

Binding Specificity: AA 76-105, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LZTS1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human LZTS1 (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 76-105 amino acids from the N-terminal region of human LZTS1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for LZTS1

Target: LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))

Alternative Name: LZTS1 (LZTS1 Products)

Synonyms: F37 antibody, FEZ1 antibody, Psdzip70 antibody, LZTS1 antibody, f37 antibody, fez1 antibody, leucine zipper tumor suppressor 1 antibody, leucine zipper, putative tumor suppressor 1 antibody, LZTS1 antibody, Lzts1 antibody, lzts1 antibody

Background: This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.Synonyms: F37/esophageal cancer-related gene-coding leucine-zipper motif, FEZ1, LZTS1, Leucine zipper putative tumor suppressor 1

Molecular Weight: 66613 Da

Gene ID: 11178

NCBI Accession: NP_066300

Pathways: Synaptic Membrane