MARCH7 antibody (N-Term)

Catalog No. ABIN953317

Product Details anti-MARCH7 Antibody

Target: MARCH7 (Membrane-Associated Ring Finger (C3HC4) 7, E3 Ubiquitin Protein Ligase (MARCH7))

Binding Specificity: AA 66-95, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCH7 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human MARCH7 / RNF177 (N-term). Other species not tested.

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 66-95 amino acids from the N-terminal region of human MARCH7 / RNF177

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MARCH7

Target: MARCH7 (Membrane-Associated Ring Finger (C3HC4) 7, E3 Ubiquitin Protein Ligase (MARCH7))

Alternative Name: MARCH7 / RNF177 (MARCH7 Products)

Synonyms: AXO antibody, AXOT antibody, MARCH-VII antibody, RNF177 antibody, Mar-07 antibody, MARCH7 antibody, axot antibody, axotrophin antibody, march-vii antibody, rnf177 antibody, DKFZp468P155 antibody, Axo antibody, Axot antibody, Gtrgeo17 antibody, membrane associated ring-CH-type finger 7 antibody, membrane associated ring-CH-type finger 7 S homeolog antibody, membrane-associated ring finger (C3HC4) 7 antibody, MARCH7 antibody, march7.S antibody, march7 antibody, March7 antibody

Background: MARCH7 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004 [PubMed 14722266]).Synonyms: AXOT, Axotrophin, E3 ubiquitin-protein ligase MARCH7, MARCH-VII, Membrane-associated RING finger protein 7, Membrane-associated RING-CH protein VII, RING finger protein 177

Molecular Weight: 78051 Da

Gene ID: 64844

NCBI Accession: NP_073737