NPHP3 antibody (N-Term)

Catalog No. ABIN953650

Product Details anti-NPHP3 Antibody

Target: NPHP3 (Nephronophthisis 3 (Adolescent) (NPHP3))

Binding Specificity: AA 151-181, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPHP3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to NPHP3.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 151-181 amino acids from the N-terminal region of human NPHP3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for NPHP3

Target: NPHP3 (Nephronophthisis 3 (Adolescent) (NPHP3))

Alternative Name: Nephrocystin 3 (NPHP3 Products)

Synonyms: si:dkey-56l10.1 antibody, MKS7 antibody, NPH3 antibody, RHPD antibody, 3632410F03Rik antibody, AI550417 antibody, C230078J01 antibody, D330020E01Rik antibody, pcy antibody, RGD1563856 antibody, nephronophthisis 3 antibody, nephrocystin 3 antibody, nephronophthisis 3 (adolescent) antibody, nphp3 antibody, NPHP3 antibody, Nphp3 antibody

Background: This gene encodes a protein containing a coiled-coil (CC) domain, a tubulin-tyrosine ligase (TTL) domain, and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin and may function in renal tubular development and function. Mutations in this gene are associated with nephronophthisis type 3. Multiple splice variants have been described but their full-length nature has not been determined.Synonyms: KIAA2000, NPHP3

Molecular Weight: 71kd Isoform 3. 150864 Da

Gene ID: 27031

NCBI Accession: NP_694972

Pathways: cAMP Metabolic Process