TNFRSF6B antibody (N-Term)

Catalog No. ABIN955277

Product Details anti-TNFRSF6B Antibody

Target: TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))

Binding Specificity: AA 29-57, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFRSF6B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects TNFRSF6B / DCR3 (N-term).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human TNFRSF6B

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for TNFRSF6B

Target: TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))

Alternative Name: TNFRSF6B / DCR3 (TNFRSF6B Products)

Synonyms: DCR3 antibody, DJ583P15.1.1 antibody, M68 antibody, M68E antibody, TR6 antibody, dcr3 antibody, m68 antibody, tr6 antibody, TNF receptor superfamily member 6b antibody, tumor necrosis factor receptor superfamily, member 11b antibody, regulator of telomere elongation helicase 1 antibody, TNF receptor superfamily member 6b L homeolog antibody, TNFRSF6B antibody, tnfrsf11b antibody, RTEL1 antibody, tnfrsf6b antibody, tnfrsf6b.L antibody

Background: This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5' UTR, have been observed for this gene.Synonyms: Decoy receptor 3, Decoy receptor for Fas ligand

Gene ID: 8771

NCBI Accession: NP_003814