ZNRF1 antibody (Middle Region)

Catalog No. ABIN955754

Product Details anti-ZNRF1 Antibody

Target: ZNRF1 (Zinc and Ring Finger Protein 1 (ZNRF1))

Binding Specificity: AA 58-86, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNRF1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects ZNRF1 (Center).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 58-86 amino acids from the Central region of human ZNRF1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for ZNRF1

Target: ZNRF1 (Zinc and Ring Finger Protein 1 (ZNRF1))

Alternative Name: ZNRF1 (ZNRF1 Products)

Synonyms: NIN283 antibody, B830022L21Rik antibody, Rnf42 antibody, Zrfp1 antibody, nin283 antibody, zgc:77896 antibody, zrfp1 antibody, zinc and ring finger 1 antibody, zinc and ring finger 1, E3 ubiquitin protein ligase S homeolog antibody, ZNRF1 antibody, Znrf1 antibody, znrf1 antibody, znrf1.S antibody

Background: In a study identifying genes in rat that are upregulated in response to nerve damage, a gene which is highly expressed in ganglia and in the central nervous system was found. The protein encoded by the rat gene contains both a zinc finger and a RING finger motif and is localized in the endosome/lysosome compartment, indicating that it may be involved in ubiquitin-mediated protein modification. The protein encoded by this human gene is highly similar in sequence to that encoded by the rat gene.Synonyms: E3 ubiquitin-protein ligase ZNRF1, NIN283, Nerve injury-induced gene 283 protein, Zinc/RING finger protein 1

Gene ID: 84937

NCBI Accession: NP_115644