Prekallikrein antibody

Catalog No. ABIN957885

Product Details anti-Prekallikrein Antibody

Target: Prekallikrein (PK)

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Prekallikrein antibody is un-conjugated

Application: Immunodiffusion (ID), Immunoelectrophoresis (IEP)

Specificity: Human Prekallikrein. The defined antibody specificity is to prekallikrein. Plasma kallikrein is present in two slightly different forms. This corresponds with two different forms of kallikrein after prekallikrein has been activated by Factor XIIa. Inactive plasma prekallikrein and active kallikrein may react with the antiserum. Although prekallikrein exhibits structural homology to Factor XI, the antiserum does not react with Factor XI. Cross-reactivity The antiserum does not cross-react with any other human plasma proteins as tested in gel- diffusion techniques. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins, since homologous proteins of different species frequently share antigenic determinants. Cross-reactivity of this antiserum has not been tested in detail, however in double radial immunodiffusion a reaction with monkey has been observed.

Purification: Immunoaffinity absorbed

Immunogen: Human prekallikrein

Type of Immunogen: Purified protein

Application Details

Application Notes: Approved: ID, IE

Usage: This product is intended for use as precipitating antiserum in electroimmunodiffusion, immunoelectrophoresis and radial immunodiffusion. This does not exclude the use of the antiserum in more sensitive techniques if proper controls are included.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Sterile distilled water 1 ml

Concentration: Lot specific

Buffer: Lyophilized antiserum

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C
Short term: +4°C. Avoid repeat freeze-thaw cycles.

Target Details for Prekallikrein

Target: Prekallikrein (PK)

Alternative Name: Prekallikrein (PK Products)

Synonyms: APS antibody, KLK2A1 antibody, PSA antibody, hK3 antibody, kallikrein related peptidase 3 antibody, KLK3 antibody