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CCL3 antibody

CCL3 Reactivity: Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN964781
  • Target See all CCL3 Antibodies
    CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
    Reactivity
    • 58
    • 22
    • 19
    • 3
    • 2
    Mouse
    Host
    • 61
    • 27
    • 2
    • 2
    • 1
    Rabbit
    Clonality
    • 68
    • 25
    Polyclonal
    Conjugate
    • 53
    • 13
    • 7
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCL3 antibody is un-conjugated
    Application
    • 65
    • 54
    • 20
    • 18
    • 8
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    Specificity
    This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above. This antibody is specific for mouse MIP-1alpha protein. Cross-reactivity with MIP-1alpha from other sources has not been determined.
    Characteristics
    Mouse MIP-1alpha, or Ccl3, of the intercrine beta (chemokine CC family) is a secreted cytokine with inflammatory, pyrogenic and chemokinetic properties. It is expressed in lung, spleen, and pancreas, and has a potent chemotactic activity for eosinophils. Ccl3 binding to a high-affinity receptor activates calcium release in neutrophils.
    Purification
    purified
    Immunogen
    This IgG fraction antibody was prepared from rabbit antiserum after repeated immunizations with recombinant truncated mouse MIP-1alpha protein produced in E.coli.
    Immunogen Type: RecombinantProtein
    Isotype
    IgG
    Top Product
    Discover our top product CCL3 Primary Antibody
  • Application Notes
    This purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 7-8 kDa in size corresponding to the mature 92 amino acid mouse MIP-1α/Ccl3 protein by western blotting in appropriate cell lysate or extract.
    Comment

    Gene Name: Ccl3

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
    Concentration
    1.0 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Preservative
    Without preservative
    Storage
    4 °C/-20 °C
    Storage Comment
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is six (6) months from date of opening.
    Expiry Date
    6 months
  • Target
    CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
    Alternative Name
    MIP-1 alpha (CCL3 Products)
    Synonyms
    MIP-1alpha antibody, G0S19-1 antibody, LD78ALPHA antibody, MIP-1-alpha antibody, MIP1A antibody, SCYA3 antibody, MIP-1a antibody, Scya3 antibody, AI323804 antibody, LD78alpha antibody, MIP1-(a) antibody, MIP1-alpha antibody, Mip1a antibody, CCL3L1 antibody, CCL3L3 antibody, chemokine (C-C motif) ligand 3 antibody, C-C motif chemokine ligand 3 antibody, CCL3 antibody, Ccl3 antibody
    Background
    Mouse MIP-1α, or Ccl3, of the intercrine beta (chemokine CC family) is a secreted cytokine with inflammatory, pyrogenic and chemokinetic properties. It is expressed in lung, spleen, and pancreas, and has a potent chemotactic activity for eosinophils. Ccl3 binding to a high-affinity receptor activates calcium release in neutrophils.
    Synonyms: Mouse Macrophage Inflammatory Protein-1-alpha, Ccl3 cytokine, C-C motif chemokine 3, Small-inducible cytokine A3, Macrophage inflammatory protein 1-α, MIP-1-alpha, TY-5, SIS-alpha, Heparin-binding chemotaxis protein, L2G25B, Scya3 protein
    Gene ID
    20302
    NCBI Accession
    NP_035467
    UniProt
    P10855
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Autophagy
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