ATF2 antibody (Activating Transcription Factor 2) (pThr51)

Details for Product anti-ATF2 Antibody No. ABIN965607, Supplier: Log in to see
Antigen
  • CRE-BP1
  • CREB2
  • HB16
  • TREB7
  • CG12850
  • CG3749
  • dATF-2
  • DmelCG30420
  • CG30420
  • CHN1
  • Atf-2
  • CRE-BP
  • Creb2
  • D130078H02Rik
  • D18875
  • Tg(Gzma-Klra1)7Wum
  • mXBP
  • atf2-A
  • atf2l
  • activating transcription factor 2
  • Activating transcription factor-2
  • activating transcription factor 2 S homeolog
  • ATF2
  • Atf-2
  • Atf2
  • atf2.S
  • atf2
Alternatives
anti-Human ATF2 antibody for Western Blotting
Epitope
pThr51, pThr69
84
53
41
37
36
36
36
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35
34
34
23
21
17
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13
10
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3
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2
1
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Reactivity
Human, Mouse (Murine), Rat (Rattus)
713
440
402
29
21
17
14
11
10
9
5
5
2
2
2
1
1
Host
Rabbit
636
56
19
4
Conjugate
This ATF2 antibody is un-conjugated
16
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10
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3
1
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Application
Immunohistochemistry (IHC)
525
340
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118
95
24
22
15
12
11
6
3
2
2
1
1
Options
Supplier
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human ATF-2 around the phosphorylation site of threonine 69 or 51 (D-Q-TP-P-T).
Specificity ATF-2 (hosphor-Thr69 or 51) antibody detects endogenous levels of ATF-2 only when phosphorylated at threonine 69 or 51.
Plasmids, Primers & others Plasmids, Primers & others ATF2 products on genomics-online (e.g. as negative or positive controls)
Antigen Activating Transcription Factor 2 (ATF2)
Alternative Name ATF2 (ATF2 Antibody Abstract)
Pathways MAPK Signaling, RTK Signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Background publications Sevilla, Santos, Vega, Lazo: "Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK." in: The Journal of biological chemistry, Vol. 279, Issue 26, pp. 27458-65, 2004 (PubMed).

Gupta, Campbell, Dérijard, Davis: "Transcription factor ATF2 regulation by the JNK signal transduction pathway." in: Science (New York, N.Y.), Vol. 267, Issue 5196, pp. 389-93, 1995 (PubMed).

Abdel-Hafiz, Heasley, Kyriakis, Avruch, Kroll, Johnson, Hoeffler: "Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases." in: Molecular endocrinology (Baltimore, Md.), Vol. 6, Issue 12, pp. 2079-89, 1993 (PubMed).

Product cited in: Alsayed, Uddin, Mahmud, Lekmine, Kalvakolanu, Minucci, Bokoch, Platanias: "Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to all-trans-retinoic acid." in: The Journal of biological chemistry, Vol. 276, Issue 6, pp. 4012-9, 2001 (PubMed).

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