S100A6 antibody

Catalog No. ABIN965737

Product Details anti-S100A6 Antibody

Target: S100A6 (S100 Calcium Binding Protein A6 (S100A6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This S100A6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: GSTs Resin purified truncated recombinant calcyclin expressed in E. Coli strain BL21 (DE3)

Purification: Antibodies are purified by protein A affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Western Blot: Dilution 1: 200- 1: 1,000
IHC(P): Dilution 1: 100- 1: 500
IHC(F): Dilution 1: 100- 1: 500
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Storage: -20 °C

References for anti-S100A6 antibody (ABIN965737)

Hwang, Lee, Kim, Li, Jin, Rhee, Kim, Lim: "Calcyclin, a Ca2+ ion-binding protein, contributes to the anabolic effects of simvastatin on bone." in: The Journal of biological chemistry, Vol. 279, Issue 20, pp. 21239-47, (2004) (PubMed).

Target Details for S100A6

Target: S100A6 (S100 Calcium Binding Protein A6 (S100A6))

Alternative Name: Calcyclin (S100A6 Products)

Synonyms: S100A6 antibody, 2A9 antibody, 5B10 antibody, CABP antibody, CACY antibody, PRA antibody, CALCYCLIN antibody, Cacy antibody, S100 calcium binding protein A6 antibody, uncharacterized LOC618256 antibody, S100 calcium binding protein A6 (calcyclin) antibody, S100A6 antibody, S100a6 antibody, LOC618256 antibody

Background: Calcyclin encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.

Gene ID: 27101

Pathways: S100 Proteins