Cyclin B1 antibody

Catalog No. ABIN965756

Product Details anti-Cyclin B1 Antibody

Target: Cyclin B1 (CCNB1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cyclin B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human CCNB1 expressed in E. Coli.

Clone: 1B10

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-Cyclin B1 antibody (ABIN965756)

Mazure, Breton, Cancer, Mellado, Abilés, Avilés, Escarti, Ginés, Alvarez, Paez, Velasco, Pavón, Miras, Martínez Olmo, Culebras,: "[Intragastric balloon in obesity treatment]." in: Nutrición hospitalaria : organo oficial de la Sociedad Española de Nutrición Parenteral y Enteral, Vol. 24, Issue 2, pp. 138-43, (2009) (PubMed).

Target Details for Cyclin B1

Target: Cyclin B1 (CCNB1)

Alternative Name: CCNB1 (CCNB1 Products)

Synonyms: ccnb antibody, cycb antibody, cb267 antibody, cycb1 antibody, wu:fa19g04 antibody, wu:fb16d01 antibody, wu:fb16e07 antibody, wu:fi21c01 antibody, ccnb1 antibody, MGC53596 antibody, CCNB antibody, Ccnb1-rs1 antibody, Ccnb1-rs13 antibody, CycB1 antibody, Cycb-4 antibody, Cycb-5 antibody, Cycb1-rs1 antibody, cyclin B1 antibody, cyclin B1 S homeolog antibody, ccnb1 antibody, ccnb1.2 antibody, ccnb1.S antibody, CCNB1 antibody, Ccnb1 antibody, ccnb1.2.S antibody

Background: The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. It has higher expression in tumor tissues .
Synonyms: CCNB, CCNB1

Molecular Weight: 60kDa

Gene ID: 891

Pathways: Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase