CHML antibody (C-Term)

Catalog No. ABIN965893

Product Details anti-CHML Antibody

Target: CHML (Choroideremia-Like (Rab Escort Protein 2) (CHML))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHML antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of mouse CHML (Choroideraemia-like protein) or Rep2 (Rab proteins geranylgeranyltransferase component A 2)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for CHML

Target: CHML (Choroideremia-Like (Rab Escort Protein 2) (CHML))

Alternative Name: CHML (CHML Products)

Synonyms: AI450814 antibody, E030003F13Rik antibody, REP-2 antibody, Rep2 antibody, REP2 antibody, choroideremia-like antibody, CHM like, Rab escort protein 2 antibody, Chml antibody, CHML antibody

Background: CHML(Choroideraemia-like protein) or Rep2 (Rab proteins geranylgeranyltransferase component A 2) binds unprenylated Rab proteins, presents it to the catalytic Rab GGTase dimer, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. It is less effective than REP-1 in supporting prenylation of Rab3 family. The protein interacts with Rab and Rab GGTase.