Purified by antigen-specific affinity chromatography.
Immunogen
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human COL15A1(Collagen alpha1(XV) chain precursor)
COL15A1
Reactivity: Human
Host: Rabbit
Polyclonal
Alexa Fluor 750
Application Notes
ELISA, Western blotting: 1µg/ml for 2hrs.
Restrictions
For Research Use only
Format
Liquid
Buffer
This antibody is stored in PBS, 50% glycerol
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Ramchandran, Dhanabal, Volk, Waterman, Segal, Lu, Knebelmann, Sukhatme: "Antiangiogenic activity of restin, NC10 domain of human collagen XV: comparison to endostatin." in: Biochemical and biophysical research communications, Vol. 255, Issue 3, pp. 735-9, (1999) (PubMed).
Myers, Kivirikko, Gordon, Dion, Pihlajaniemi: "Identification of a previously unknown human collagen chain, alpha 1(XV), characterized by extensive interruptions in the triple-helical region." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 21, pp. 10144-8, (1992) (PubMed).
COL15A1 antibody, col115a1 antibody, col15a1 antibody, col15a1l antibody, sb:cb605 antibody, collagen type XV alpha 1 chain antibody, collagen, type XV, alpha 1a antibody, collagen, type XV, alpha 1 antibody, COL15A1 antibody, col15a1a antibody, Col15a1 antibody
Background
COL15A1(Collagen alpha-1(XV) is a structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle. Endostatin potently inhibits angiogenesis. COL15A1 is expressed predominantly in internal organs such as adrenal gland, pancreas and kidney. It belongs to the fibril-associated collagens with interrupted helices (FACIT) family. It contains 1 TSP N-terminal (TSPN) domain.