SLC31A2 antibody (N-Term)

Catalog No. ABIN965919

Product Details anti-SLC31A2 Antibody

Target: SLC31A2 (Solute Carrier Family 31 (Copper Transporters), Member 2 (SLC31A2))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC31A2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human COPT2(copper transporter 2)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for SLC31A2

Target: SLC31A2 (Solute Carrier Family 31 (Copper Transporters), Member 2 (SLC31A2))

Alternative Name: COPT2 (SLC31A2 Products)

Synonyms: COPT2 antibody, CTR2 antibody, hCTR2 antibody, ctr2 antibody, xem1 antibody, copt2 antibody, SLC31A2 antibody, AI604396 antibody, copper transporter 2 antibody, solute carrier family 31 member 2 antibody, solute carrier family 31 member 2 S homeolog antibody, solute carrier family 31, member 2 antibody, copper transporter 2 antibody, SLC31A2 antibody, slc31a2.S antibody, slc31a2 antibody, Slc31a2 antibody, COPT2 antibody

Background: The COPT2(copper transporter 2) is involved in low-affinity copper uptake. COPT2 is a multi-pass membrane protein and belongs to the SLC31A transporter family. The redox active metal copper is an essential cofactor in critical biological processes such as respiration, iron transport,oxidative stress protection, hormone production, and pigmentation. A widely conserved family of high-affinity copper transport proteins (Ctr proteins) mediates copper uptake at the plasma membrane. A series of clustered methionine residues in the hydrophilic extracellular domain, and an MXXXM motif in the second transmembrane domain, are important for copper uptake. These methionine probably coordinate copper during the process of metal transport