EGFR antibody (Epidermal Growth Factor Receptor) (pTyr869)

Details for Product anti-EGFR Antibody No. ABIN966039
Antigen
  • C-erb
  • CG10079
  • D-EGFR
  • D-Egf
  • DEGFR
  • DER
  • DER flb
  • DER/EGFR
  • DER/faint little ball
  • DER/top
  • DER/torpedo
  • DER1
  • DEgfr
  • Degfr
  • Der
  • DmHD-33
  • Dmel\\CG10079
  • EFG-R
  • EGF-R
  • EGFR
  • EGFr
  • EGfr
  • EK2-6
  • Egf
  • Egf-r
  • EgfR
  • El
  • Elp
  • Elp-1
  • Elp-B1
  • Elp-B1RB1
  • HD-33
  • TOP
  • Torpedo/DER
  • Torpedo/Egfr
  • c-erbB
  • d-egf-r
  • dEGFR
  • dEGFR1
  • dEgfr
  • der
  • egfr
  • flb
  • l(2)05351
  • l(2)09261
  • l(2)57DEFa
  • l(2)57EFa
  • l(2)57Ea
  • mor1
  • top
  • top/DER
  • top/flb
  • torpedo/Egfr
  • torpedo/egfr
  • EGFR12
  • EGFR15
  • egfr1
  • Erbb2
  • ERBB
  • ERBB1
  • HER1
  • PIG61
  • mENA
  • ErbB-1
  • Errp
  • 9030024J15Rik
  • AI552599
  • Erbb
  • Errb1
  • Wa5
  • wa-2
  • wa2
  • epidermal growth factor receptor
  • Epidermal growth factor receptor
  • epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
  • EGFR
  • Egfr
  • egfra
  • egfr1
  • LOC5564544
Alternatives
anti-Human EGFR antibody for Immunoprecipitation
Epitope
pTyr869
76
75
67
65
63
62
61
60
57
54
42
41
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36
34
30
30
24
24
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12
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3
2
2
2
2
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2
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2
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2
2
2
2
2
2
2
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2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
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1
1
1
1
1
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1
1
1
1
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1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
2131
847
782
29
23
20
18
16
14
7
4
3
2
2
2
2
2
2
1
1
1
1
Host
Rabbit
1488
597
23
19
16
5
2
1
1
1
Conjugate
This EGFR antibody is un-conjugated
100
53
52
43
43
41
41
41
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41
34
30
16
16
16
16
16
10
8
8
8
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8
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8
8
8
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Immunohistochemistry (IHC)
1279
553
544
353
327
253
233
210
86
66
65
52
37
35
24
18
14
11
9
6
6
4
4
3
3
3
3
3
2
2
2
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1
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1
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1
Options
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human EGFR around the phosphorylation site of tyrosine 869 (K-E-YP-H-A).
Specificity EGFR (phospho-Tyr869) antibody detects endogenous levels of EGFR only when phosphorylated at tyrosine 869.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using nonphosphopeptide corresponding to the phosphorylation site.
Plasmids, Primers & others Plasmids, Primers & others EGFR products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name EGFR (EGFR Antibody Abstract)
Pathways NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation
Application Notes WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Background publications Glickman, Adir: "The proteasome and the delicate balance between destruction and rescue." in: PLoS biology, Vol. 2, Issue 1, pp. E13, 2004 (PubMed).

Wu, Castle: "Tyrosine phosphorylation of selected secretory carrier membrane proteins, SCAMP1 and SCAMP3, and association with the EGF receptor." in: Molecular biology of the cell, Vol. 9, Issue 7, pp. 1661-74, 1999 (PubMed).

Product cited in: Yamamasu, Sato, Ogita, Inoue: "Role of glutathione metabolism and apoptosis in the regression of liver hemopoiesis." in: Free radical biology & medicine, Vol. 23, Issue 1, pp. 100-9, 1997 (PubMed).

ORourke, Qian, Zhang, Davis, Nute, Meinkoth, Greene: "Trans receptor inhibition of human glioblastoma cells by erbB family ectodomains." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 7, pp. 3250-5, 1997 (PubMed).

Goldstein, Li, Wang, Heidaran, Aaronson, Shinn, Schlegel, Pierce et al.: "The bovine papillomavirus type 1 E5 transforming protein specifically binds and activates the beta-type receptor for the platelet-derived growth factor but not other related tyrosine ..." in: Journal of virology, Vol. 68, Issue 7, pp. 4432-41, 1994 (PubMed).

Kanner, Reynolds, Parsons: "Tyrosine phosphorylation of a 120-kilodalton pp60src substrate upon epidermal growth factor and platelet-derived growth factor receptor stimulation and in polyomavirus middle-T-antigen-transformed cells." in: Molecular and cellular biology, Vol. 11, Issue 2, pp. 713-20, 1991 (PubMed).

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