EPHA1 antibody

Catalog No. ABIN966070

Product Details anti-EPHA1 Antibody

Target: EPHA1 (Ephrin Type A Receptor 1 (EPHA1))

Reactivity: Human

Host: Please inquire

Clonality: Monoclonal

Conjugate: This EPHA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: Ni-NTA purified truncated recombinant EphA1 expressed in E. Coli strain BL21 (DE3)

Purification: Antibodies are purified by protein A affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Western Blot: 1: 200- 1: 1,000
IHC-P: 1: 200- 1: 1,000
IHC-F: 1: 200- 1: 1,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Storage: -20 °C

References for anti-EPHA1 antibody (ABIN966070)

Duffy, Steiner, Tam, Boyd: "Expression analysis of the Epha1 receptor tyrosine kinase and its high-affinity ligands Efna1 and Efna3 during early mouse development." in: Gene expression patterns : GEP, Vol. 6, Issue 7, pp. 719-23, (2006) (PubMed).

Pasquale: "Eph receptor signalling casts a wide net on cell behaviour." in: Nature reviews. Molecular cell biology, Vol. 6, Issue 6, pp. 462-75, (2005) (PubMed).

Target Details for EPHA1

Target: EPHA1 (Ephrin Type A Receptor 1 (EPHA1))

Alternative Name: EphA1 (EPHA1 Products)

Synonyms: EPH antibody, EPHT antibody, EPHT1 antibody, 5730453L17Rik antibody, AL033318 antibody, Eph antibody, Esk antibody, EPHA9 antibody, EPH receptor A1 antibody, Eph receptor A1 antibody, EPHA1 antibody, Epha1 antibody

Background: EPH receptor A1 (EphA1), with 976-amino acid protein(about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date and their ligands, the ephrins,can be subdivided into two major subclasses, ephrin-A and ephrin-B. Interaction of Eph receptor tyrosine kinases with their membrane bound ephrin ligands initiates bidirectional signaling events that regulate cell migratory and adhesive behavior, particularly in the nervous system. They have been implicated in various developmental processes, including axonal guidance, angiogenesis, morphogenesis and carcinogenesis.

Gene ID: 2041